SCHEMBL955878

SCHEMBL955878

CCOP(C)(=O)SCCN(CC)CC

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 1/20 0.38
TSHR P16473 2/20 0.34
TP53 P04637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18502525 1.00 MEN1 (0.38) MEN1GAACYP2C9CYP2C19KMT2A
SCHEMBL10058453 0.87 TSHR (0.35) MEN1GAACYP2C9CYP2C19KMT2A
SCHEMBL7869696 0.82 MEN1 (0.39) MEN1GAACYP2C9CYP2C19KMT2A
SCHEMBL29394016 0.82 TSHR (0.36) MEN1KMT2ATSHRTP53TDP1
SCHEMBL121180 0.82 MEN1 (0.39) MEN1GAACYP2C9CYP2C19KMT2A
SCHEMBL18295171 0.82
SCHEMBL21362842 0.82 CYP3A4 (0.42) TSHR
SCHEMBL961275 0.82
SCHEMBL5599016 0.81 MEN1 (0.38) MEN1GAACYP2C9CYP2C19KMT2A
SCHEMBL20798220 0.79 MEN1 (0.37) MEN1GAACYP2C9CYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12318435-B2 Recombinant protein produced from cholinesterase gene derived from Pseudomonas aeruginosa and the composition comprising the same for treating or preventing a neurological disease SKYPEACH CO., LTD. (KR) 2025-06-03 US claimed
CN-118114335-A Building carbon emission prediction method and system based on database platform 陕西建工控股集团未来城市创新科技有限公司 2024-05-31 CN claimed
US-20230270750-A1 CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2023-08-31 US claimed
EP-4188919-A1 CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS Etat Français représenté par la Direction Centrale Du Service de Santé des Armées (FR) 2023-06-07 EP claimed
US-20230026578-A1 A recombinant protein produced from cholinesterase gene derived from Pseudomonas aeruginosa and the composition comprising the same for treating or preventing a neurological disease SKYPEACH CO., LTD (KR) 2023-01-26 US claimed
US-20220087980-A1 METHODS OF USING DANTROLENE TO TREAT NERVE AGENT EXPOSURE EAGLE PHARMACEUTICALS, INC. 2022-03-24 US claimed
US-20210041339-A1 METHODS FOR DETECTION OF THE PERMEATION OF CHEMICAL WARFARE AGENTS THROUGH MEMBRANES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY 2021-02-11 US claimed
US-20200383954-A1 METHODS OF USING DANTROLENE TO TREAT NERVE AGENT EXPOSURE EAGLE PHARMACEUTICALS, INC. 2020-12-10 US claimed
US-10801987-B2 2H to 1T phase based transition metal dichalcogenide sensor for optical and electronic detection of strong electron donor chemical vapors THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2020-10-13 US claimed
US-10722743-B2 Multicatalyst polyelectrolyte membranes and materials and methods utilizing the same RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2020-07-28 US claimed
US-20200163952-A1 COMPOSITIONS AND METHODS FOR TREATING NERVE AGENT EXPOSURE HOFFMAN STEVEN (US) 2020-05-28 US claimed
US-10421952-B1 Mutant organophosphorus acid anhydrolase enzymes having increased catalytic efficiency on V-agents THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 2019-09-24 US claimed
WO-2019050923-A1 METHODS OF USING DANTROLENE TO TREAT NERVE AGENT EXPOSURE EAGLE PHARMACEUTICALS, INC. (US) 2019-03-14 WO claimed
US-20180024085-A1 2H TO 1T PHASE BASED TRANSITION METAL DICHALCOGENIDE SENSOR FOR OPTICAL AND ELECTRONIC DETECTION OF STRONG ELECTRON DONOR CHEMICAL VAPORS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2018-01-25 US claimed
US-20170007871-A1 Multicatalyst Polyelectrolyte Membranes and Materials and Methods Utilizing the Same DEFENSE THREAT REDUCTION AGENCY, US DOD 2017-01-12 US claimed
US-20150038588-A1 COMPOSITIONS AND METHODS OF TREATMENT OF STATUS EPILEPTICUS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2015-02-05 US claimed
EP-2822655-A1 COMPOSITIONS AND METHODS OF TREATMENT OF STATUS EPILEPTICUS Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2015-01-14 EP claimed
WO-2013132490-A1 COMPOSITIONS AND METHODS OF TREATMENT OF STATUS EPILEPTICUS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2013-09-12 WO claimed
EP-1928560-A2 ENZYMES AND FORMULATIONS FOR BROAD-SPECIFICITY DECONTAMINATION OF CHEMICAL AND BIOLOGICAL WARFARE AGENTS Verenium Corporation (US) 2008-06-11 EP claimed
WO-2008036061-A2 ENZYMES AND FORMULATIONS FOR BROAD-SPECIFICITY DECONTAMINATION OF CHEMICAL AND BIOLOGICAL WARFARE AGENTS VERENIUM CORPORATION (US) 2008-03-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220087980-A1 METHODS OF USING DANTROLENE TO TREAT NERVE AGENT EXPOSURE PMP22, CNTN1, SMN1; SMN2 MEN1 1585/4885GAA 2045/4885CYP2C9 3587/4885
US-20230270750-A1 CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS BCHE, ACHE, CHAT MEN1 3307/4885GAA 507/4885CYP2C9 101/4885
US-20150038588-A1 COMPOSITIONS AND METHODS OF TREATMENT OF STATUS EPILEPTICUS CHRNA3, GAP43, CHRNA5 MEN1 3486/4885GAA 2656/4885CYP2C9 858/4885
US-20200383954-A1 METHODS OF USING DANTROLENE TO TREAT NERVE AGENT EXPOSURE PMP22, CNTN1, SMN1; SMN2 MEN1 1585/4885GAA 2045/4885CYP2C9 3587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.