SCHEMBL9558992

SCHEMBL9558992

CCOc1ccc(C(C(C)C)C(Cc2ccc(F)c(Oc3ccccc3)c2)OC(Cc2ccc(F)c(Oc3ccccc3)c2)C(c2ccc(OCC)cc2)C(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.41
PTGS2 P35354 3/20 0.36
LMNA P02545 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SIGMAR1 Q99720 1/20 0.35
CACNA1C Q13936 1/20 0.35
PPARG P37231 2/20 0.34
PPARD Q03181 2/20 0.34
PPARA Q07869 2/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
CNR2 P34972 1/20 0.34
KLKB1 P03952 1/20 0.34
PTGS1 P23219 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8846649 0.81 LTA4H (0.43) LTA4HPTGS2LMNAMEN1KMT2A
SCHEMBL7950948 0.81 LTA4H (0.43) LTA4HPTGS2LMNAMEN1KMT2A
SCHEMBL9331962 0.80 LTA4H (0.43) LTA4HPTGS2LMNAMEN1KMT2A
SCHEMBL10549349 0.77 LTA4H (0.41) LTA4HLMNAMEN1KMT2AL3MBTL1
SCHEMBL10835508 0.77 LTA4H (0.41) LTA4HPTGS2LMNAMEN1KMT2A
SCHEMBL9331956 0.77 LTA4H (0.43) LTA4HLMNAL3MBTL1PPARGPPARD
SCHEMBL7929051 0.76 LTA4H (0.53) LTA4HPTGS2LMNAMEN1KMT2A
SCHEMBL9031229 0.76 LTA4H (0.42) LTA4HLMNAMEN1KMT2AL3MBTL1
SCHEMBL7626911 0.76 LTA4H (0.39) LTA4HPTGS2LMNAMEN1KMT2A
SCHEMBL7623050 0.76 LTA4H (0.39) LTA4HPTGS2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed