SCHEMBL8846649

SCHEMBL8846649

CCOc1ccc(C(Cc2ccc(F)c(Oc3ccccc3)c2)C(C)(C)[SiH3])cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.43
LMNA P02545 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
SIGMAR1 Q99720 1/20 0.36
CACNA1C Q13936 1/20 0.36
MAPT P10636 2/20 0.36
ATM Q13315 1/20 0.36
PTGS2 P35354 1/20 0.35
PPARG P37231 2/20 0.35
PPARD Q03181 2/20 0.35
PPARA Q07869 2/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
CNR2 P34972 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8613003 0.83 LTA4H (0.51) LTA4HSIGMAR1PPARGPPARACNR2
SCHEMBL7950948 0.83 LTA4H (0.43) LTA4HLMNAL3MBTL1KMT2AMEN1
SCHEMBL9331962 0.81 LTA4H (0.43) LTA4HLMNAL3MBTL1KMT2AMEN1
SCHEMBL9558992 0.81 LTA4H (0.41) LTA4HLMNAL3MBTL1KMT2AMEN1
SCHEMBL9031229 0.80 LTA4H (0.42) LTA4HLMNAL3MBTL1KMT2AMEN1
SCHEMBL9801523 0.79 LTA4H (0.43) LTA4HLMNAL3MBTL1KMT2AMEN1
SCHEMBL409992 0.79 LTA4H (0.41) LTA4HLMNAL3MBTL1KMT2AMEN1
SCHEMBL407786 0.79 LTA4H (0.41) LTA4HLMNAL3MBTL1KMT2AMEN1
SCHEMBL9331956 0.78 LTA4H (0.43) LTA4HLMNAL3MBTL1PPARGPPARD
SCHEMBL7929051 0.78 LTA4H (0.53) LTA4HLMNAL3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5635217-A IMPREGNATING WITH A COPPER COMPOUND, AN ALKANOLAMINE, AN EMULSIFIER AND/OR A PHOSPHONIUM COMPOUND DR. WOLMAN GMBH (DE) 1997-06-03 US disclosed