SCHEMBL9559014

SCHEMBL9559014

C=C(C)C(C(=O)OCc1cccc(Oc2ccccc2)c1)c1ccc(OC)c(OC)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
ACHE P22303 1/20 0.45
FFAR1 O14842 5/20 0.43
TDP1 Q9NUW8 2/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
HDAC8 Q9BY41 1/20 0.42
FFAR4 Q5NUL3 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP12 P39900 1/20 0.42
FKBP1A P62942 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
LMNA P02545 1/20 0.41
ADRA2A P08913 1/20 0.41
CNR1 P21554 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9557937 0.88 MMP1 (0.47) MMP1FFAR1TDP1MMP2MMP9
SCHEMBL9558216 0.88 FFAR1 (0.47) MMP1CA1CA2ACHEFFAR1
SCHEMBL9558474 0.84 ACHE (0.49) MMP1CA1CA2ACHEFFAR1
SCHEMBL11444823 0.80 MAPK14 (0.47) MMP1FFAR1TDP1FFAR4MMP2
SCHEMBL11204618 0.77 MMP1 (0.51) MMP1FFAR1TDP1PPARGPPARA
SCHEMBL9558250 0.75 FFAR1 (0.52) MMP1FFAR1TDP1FFAR4MMP2
SCHEMBL24404836 0.73 CA1 (0.41) CA1CA2ACHEHDAC8MEN1
SCHEMBL10795614 0.73 MMP1 (0.54) MMP1FFAR1TDP1PPARGPPARA
SCHEMBL10887508 0.73 MMP1 (0.54) MMP1FFAR1TDP1FFAR4MMP2
SCHEMBL22066497 0.73 MMP1 (0.56) MMP1FFAR1TDP1FFAR4MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0257415-B1 INSECTICIDAL RESIN COATING FILM MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-03-31 EP disclosed
US-4997650-A (Meth)acrylonitrile polymer MITSUI TOATSU CHEMICALS, INC. (JP) 1991-03-05 US disclosed
US-4818525-A LONG-LASTING; ACRYLONITRILE COPOLYMER MITSUI TOATSU CHEMICALS, INC. (JP) 1989-04-04 US disclosed
EP-0257415-A1 Insecticidal resin coating film MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-02 EP disclosed