Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9558893 | 0.90 | CCKBR (0.47) | CCKBRALDH1A1HPGDGAACA12 | |
| SCHEMBL9559037 | 0.88 | GAA (0.46) | CCKBRLMNAALDH1A1HPGDMEN1 | |
| SCHEMBL9558985 | 0.84 | CCKBR (0.46) | CCKBRALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9558855 | 0.81 | GAA (0.51) | CCKBRLMNAALDH1A1HPGDMEN1 | |
| SCHEMBL9558960 | 0.81 | CCKBR (0.46) | CCKBRALDH1A1HPGDGAACA12 | |
| SCHEMBL9558862 | 0.80 | CCKBR (0.51) | CCKBRALDH1A1HPGDKDM4EMMP1 | |
| Water SCHEMBL9559012 | 0.79 | CCKBR (0.50) | CCKBRALDH1A1HPGDKDM4EMMP1 | |
| SCHEMBL9559024 | 0.79 | CCKBR (0.46) | CCKBRALDH1A1HPGDGAACA12 | |
| SCHEMBL9559135 | 0.78 | GAA (0.49) | CCKBRALDH1A1HPGDGAACA12 | |
| SCHEMBL9559158 | 0.78 | GAA (0.48) | CCKBRLMNAALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3197453-A | — | — | None | — | — | JP | disclosed |
| US-5177069-A | Cholecystokinin inhibitor, pancreatic antisecretory agent | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| JP-H03197453-A | NAPHTHYLSULFONYLALKYLCARBOXYLIC ACID DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1991-08-28 | — | — | JP | disclosed |
| EP-0433064-A1 | Naphthylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1991-06-19 | — | — | EP | disclosed |