Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 6/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MC4R | P32245 | 2/20 | 0.34 |
| ▸ | MC5R | P33032 | 2/20 | 0.34 |
| ▸ | MC3R | P41968 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559129 | 0.84 | CCKBR (0.45) | CCKBRMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9558864 | 0.82 | CCKBR (0.48) | CCKBRPLA2G2APLA2G10ALDH1A1CYP3A4 | |
| SCHEMBL9558499 | 0.78 | CASP1 (0.41) | PLA2G2APLA2G10ALDH1A1EGFR | |
| SCHEMBL9558991 | 0.74 | PLA2G2A (0.42) | CCKBRPLA2G2APLA2G10CYP3A4CYP2C9 | |
| SCHEMBL9558893 | 0.73 | CCKBR (0.47) | CCKBRALDH1A1HPGD | |
| SCHEMBL9645604 | 0.72 | CCKBR (0.44) | CCKBRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL9559037 | 0.71 | GAA (0.46) | CCKBRMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9644811 | 0.69 | CCKAR (0.48) | CCKBRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL9645573 | 0.69 | CCKAR (0.39) | CCKBRALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL9558477 | 0.67 | PLA2G2A (0.45) | PLA2G2APLA2G10ALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5177069-A | Cholecystokinin inhibitor, pancreatic antisecretory agent | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0433064-A1 | Naphthylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1991-06-19 | — | — | EP | disclosed |