⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8691695 | 0.67 | — | — | |
| SCHEMBL11786643 | 0.67 | — | — | |
| SCHEMBL1533841 | 0.67 | PPARA (0.32) | — | |
| SCHEMBL10772455 | 0.62 | — | — | |
| SCHEMBL1004526 | 0.62 | — | — | |
| SCHEMBL635226 | 0.60 | — | — | |
| SCHEMBL17838918 | 0.60 | — | — | |
| SCHEMBL2398119 | 0.59 | — | — | |
| SCHEMBL2702676 | 0.59 | ALDH1A1 (0.33) | — | |
| SCHEMBL7113896 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710456-B | Compound, light-emitting material, and organic light-emitting element | 九州有机光材股份有限公司 | 2026-05-05 | — | — | CN | disclosed |
| US-20250129099-A1 | INHIBITOR OF APOPTOSIS (IAP) PROTEIN ANTAGONISTS | Sanford Burnham Prebys Medical Discovery Institute | 2025-04-24 | — | — | US | disclosed |
| EP-4426707-A1 | INHIBITOR OF APOPTOSIS (IAP) PROTEIN ANTAGONISTS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-09-11 | — | — | EP | disclosed |
| CN-114634502-B | 3-Aryl substituted thiazolidine-4-ketone-2-methylene hydrazono methylene-1H-indole derivative and preparation method thereof | 复旦大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-114634496-B | Indolone substituted-1, 3-thiazolidinedione derivative and preparation method and application thereof | 复旦大学 | 2024-04-19 | — | — | CN | disclosed |
| CN-114634500-B | PTP1B inhibitor and synthesis method and application thereof | 复旦大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-117362292-A | Amide derivative heat-activated delayed fluorescent material and preparation method and application thereof | 闽都创新实验室 | 2024-01-09 | — | — | CN | disclosed |
| CN-116710456-A | Compound, light-emitting material, and organic light-emitting element | 九州有机光材股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2023160708-A1 | INDOLONE-SUBSTITUTED-1,3-THIAZOLIDINONE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 复旦大学 | 2023-08-31 | — | — | WO | disclosed |
| WO-2022210606-A1 | METHOD FOR EVALUATING FUTURE RISK OF DEVELOPING DEMENTIA | 味の素株式会社 | 2022-10-06 | — | — | WO | disclosed |
| CN-112876400-B | Indole compound and preparation method and application thereof | 南方医科大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-114634502-A | 3-aryl substituted thiazolidine-4-ketone-2-ylidenehydrazonomethylene-1H-indole derivatives and preparation method thereof | 复旦大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-114634500-A | PTP1B inhibitor and synthesis method and application thereof | 复旦大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-114634496-A | Indolone substituted-1, 3-thiazolidone derivative and preparation method and application thereof | 复旦大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-111148750-A | Azithromycin derivatives containing phosphonium ions as anticancer agents | 来兴泰德基金会 | 2020-05-12 | — | — | CN | disclosed |
| EP-0327426-B1 | Indolo[3,2,1-de][1,4]-oxazino[2,3,4-ij][1,5]naphthyridine derivatives, process for their preparation and intermediates, their use as medicaments and compositions containing them | ROUSSEL UCLAF (FR) | 1993-11-03 | — | — | EP | disclosed |
| US-4904655-A | Novel indolo [3,2,1-de] [1,4] oxazino [2,3,4-ij] [1,5] | ROUSSEL UCLAF (FR) | 1990-02-27 | — | — | US | disclosed |
| EP-0327426-A1 | Indolo[3,2,1-de][1,4]-oxazino[2,3,4-ij][1,5]naphthyridine derivatives, process for their preparation and intermediates, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1989-08-09 | — | — | EP | disclosed |
| CN-86103619-A | The preparation method of the bicyclic pyrazolidinones that 7-replaces | — | 1986-10-29 | — | — | CN | disclosed |