Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.37 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021570 | 0.97 | AURKA (0.39) | AURKADAPK3MAP4K4RETIGF1R | |
| SCHEMBL9559565 | 0.85 | GABRA1 (0.35) | GABRA1GABRB2AKR1B1 | |
| SCHEMBL9559592 | 0.81 | GABRA1 (0.34) | AURKADAPK3MAP4K4RETIGF1R | |
| SCHEMBL9559591 | 0.79 | NQO1 (0.39) | GABRA1GABRB2ALDH1A1KDM4E | |
| SCHEMBL4859718 | 0.77 | AURKA (0.35) | AURKADAPK3MAP4K4RETIGF1R | |
| SCHEMBL8677546 | 0.77 | AURKA (0.35) | AURKADAPK3MAP4K4RETIGF1R | |
| SCHEMBL9559593 | 0.75 | MEN1 (0.31) | AURKADAPK3MAP4K4RETIGF1R | |
| SCHEMBL251882 | 0.75 | GABRA1 (0.44) | AURKADAPK3MAP4K4RETIGF1R | |
| SCHEMBL982140 | 0.73 | GABRA1 (0.35) | GABRA1GABRB2L3MBTL1 | |
| SCHEMBL4789832 | 0.73 | GABRA1 (0.41) | AURKADAPK3MAP4K4RETIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5235061-A | 2,4-disilaalkanes; agriculture | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1993-08-10 | — | — | US | disclosed |