SCHEMBL9559604

SCHEMBL9559604

CC(C)[C@@H]1CCC(C)(C)C[C@H]1O

nearest known ligand 0.42

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.42
TRPM8 Q7Z2W7 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18105686 1.00 TRPA1 (0.42) TRPA1TRPM8
SCHEMBL11677340 1.00 TRPA1 (0.42) TRPA1TRPM8
SCHEMBL19920235 1.00 TRPA1 (0.42) TRPA1TRPM8
SCHEMBL18105741 1.00 TRPA1 (0.42) TRPA1TRPM8
SCHEMBL18105685 1.00 TRPA1 (0.42) TRPA1TRPM8
SCHEMBL19920155 1.00 TRPA1 (0.42) TRPA1TRPM8
SCHEMBL10686598 0.86 TRPA1 (0.38) TRPA1TRPM8
Acrylic Acid SCHEMBL28486776 0.85 TRPA1 (0.33) TRPA1TRPM8
SCHEMBL340924 0.83 TRPA1 (0.42) TRPA1TRPM8
SCHEMBL12166599 0.83 TRPA1 (0.38) TRPA1TRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107532063-B Methylmenthol derivative and cold-sensitive composition containing the same 高砂香料工业株式会社 2020-03-10 CN disclosed
US-10494330-B2 Methyl menthol derivative and cooling agent composition containing same TAKASAGO INTERNATIONAL CORPORATION (JP) 2019-12-03 US disclosed
US-10494330-B2 Methyl menthol derivative and cooling agent composition containing same TAKASAGO INTERNATIONAL CORPORATION (JP) 2019-12-03 US disclosed
EP-3275962-B1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME TAKASAGO PERFUMERY CO LTD (JP) 2019-10-02 EP disclosed
EP-3275962-B1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME TAKASAGO PERFUMERY CO LTD (JP) 2019-10-02 EP disclosed
US-20180057447-A1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2018-03-01 US disclosed
US-20180057447-A1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2018-03-01 US disclosed
US-20180057447-A1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2018-03-01 US disclosed
EP-3275962-A1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME Takasago International Corporation (JP) 2018-01-31 EP disclosed
EP-3275962-A1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME Takasago International Corporation (JP) 2018-01-31 EP disclosed
CN-107532063-A Methyl menthol derivative and the cooling agent composition containing it 高砂香料工业株式会社 2018-01-02 CN disclosed
WO-2016153011-A1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME 高砂香料工業株式会社 2016-09-29 WO disclosed
EP-2789247-B1 ANTIOXIDATIVE COMPOSITION SYMRISE AG (DE) 2015-11-18 EP disclosed
EP-2789247-A1 Antioxidative composition Symrise AG (DE) 2014-10-15 EP disclosed
US-5230897-A Patch containing terpenes as penetration aid G. D. SEARLE & CO. (US) 1993-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180057447-A1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME TRPM4, TAS2R41, TRPM2 TRPA1 22/4885TRPM8 5/4885
US-10494330-B2 Methyl menthol derivative and cooling agent composition containing same TRPM4, TAS2R41, TRPM2 TRPA1 22/4885TRPM8 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.