Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681196 | 0.85 | KDM4E (0.44) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL27613224 | 0.81 | HMGCR (0.57) | KDM4EHMGCRALDH1A1MEN1KMT2A | |
| SCHEMBL1807423 | 0.81 | KDM4E (0.49) | KDM4EPOLBALDH1A1TUBB4ATUBB | |
| SCHEMBL29033634 | 0.81 | KDM4E (0.49) | KDM4EPOLBALDH1A1TUBB4ATUBB | |
| Hydrochloric Acid SCHEMBL20547016 | 0.80 | DPP4 (0.48) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL1806113 | 0.79 | KDM4E (0.60) | KDM4EPOLBALDH1A1TUBB4ATUBB | |
| SCHEMBL9752929 | 0.77 | HMGCR (0.50) | KDM4EHMGCRALDH1A1MEN1KMT2A | |
| SCHEMBL9559998 | 0.77 | CYP3A4 (0.47) | POLBHMGCRALDH1A1MEN1KMT2A | |
| SCHEMBL16168327 | 0.75 | HMGCR (0.54) | KDM4EPOLBHMGCRALDH1A1MEN1 | |
| SCHEMBL31421883 | 0.74 | ALDH1A1 (0.36) | POLBHMGCRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325247-B1 | CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-5061800-A | ANTITUMOR AGENTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0325247-A1 | Camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-07-26 | — | — | EP | disclosed |