Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752748 | 0.85 | FASN (0.55) | HMGCRMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL6863655 | 0.82 | CA9 (0.54) | HMGCRCA9MEN1KMT2ACYP3A4 | |
| SCHEMBL27842593 | 0.81 | CYP3A4 (0.53) | HMGCRMEN1KMT2ACYP3A4PTGS1 | |
| SCHEMBL8546247 | 0.80 | CYP3A4 (0.55) | HMGCRCA9KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL27613224 | 0.78 | HMGCR (0.57) | HMGCRMEN1KMT2ACYP3A4PTGS1 | |
| SCHEMBL9752827 | 0.77 | CYP3A4 (0.60) | KMT2ACYP3A4HTTGAA | |
| SCHEMBL10456723 | 0.77 | CA9 (0.49) | HMGCRCA9MEN1KMT2AKDM4E | |
| SCHEMBL9559705 | 0.77 | KDM4E (0.45) | HMGCRCA9MEN1KMT2AALDH1A1 | |
| SCHEMBL3407396 | 0.76 | MEN1 (0.65) | HMGCRMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL1662884 | 0.76 | HMGCR (0.46) | HMGCRCA9MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009595-A1 | ANTI-VIRAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |