Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.34 |
| ▸ | GBA1 | P04062 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039473 | 0.98 | TAAR1 (0.36) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6806021 | 0.94 | TAAR1 (0.40) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10879457 | 0.85 | GNAO1 (0.36) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28805455 | 0.85 | GNAO1 (0.36) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3148546 | 0.85 | TAAR1 (0.36) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9559746 | 0.80 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL28005921 | 0.77 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL5770282 | 0.76 | TAAR1 (0.42) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28084161 | 0.76 | TAAR1 (0.39) | TAAR1CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9559843 | 0.75 | CHRNB2 (0.34) | GNAO1GNAI3GNAI1CHRNB2CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200250-B1 | IMPROVING THE QUALITY OF CATALYTICALLY PREPARED POLYALKYLENE POLYAMINES | UNION CARBIDE CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| US-4827037-A | Quality of catalytically prepared polyalkylene polyamines | UNION CARBIDE CORPORATION (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0200250-A2 | Improving the quality of catalytically prepared polyalkylene polyamines | UNION CARBIDE CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |
| EP-0200251-A2 | Use of pressure to control the noncyclics/cyclics ration of polyalkylene amines | UNION CARBIDE CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |
| EP-0197613-A2 | Water addition to enhance phosphoric acid salt catalyst activity | UNION CARBIDE CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0197611-A2 | Conversion of oxygen-containing polyamines | UNION CARBIDE CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |
| EP-0197612-A2 | Interchangeable process scheme | UNION CARBIDE CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |