Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057992 | 0.88 | MGLL (0.70) | MGLLRAB9AENPP2KDM1AMAOA | |
| SCHEMBL6400257 | 0.84 | MGLL (0.72) | MGLLRAB9AENPP2KDM1AMAOA | |
| SCHEMBL9560442 | 0.82 | MGLL (0.53) | MGLLRAB9AENPP2KDM1AMAOA | |
| SCHEMBL22390191 | 0.82 | MGLL (0.53) | MGLLRAB9AENPP2KDM1AMAOA | |
| SCHEMBL22390190 | 0.82 | MGLL (0.53) | MGLLRAB9AENPP2KDM1AMAOA | |
| SCHEMBL882953 | 0.82 | MGLL (0.68) | MGLLRAB9AENPP2KDM1AMAOA | |
| SCHEMBL13655148 | 0.80 | MGLL (0.65) | MGLLRAB9AENPP2KDM1AMAOA | |
| SCHEMBL4066082 | 0.80 | MGLL (0.65) | MGLLRAB9AENPP2KDM1AMAOA | |
| SCHEMBL10013766 | 0.79 | MGLL (0.61) | MGLLRAB9AENPP2KDM1AMAOA | |
| SCHEMBL17927947 | 0.79 | MGLL (0.72) | MGLLRAB9AENPP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111108092-A | Arylamide Kv2.1 inhibitor and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2020-05-05 | — | — | CN | disclosed |
| EP-0194554-B1 | PROCESS FOR PRODUCTION OF OXIME DERIVATIVES | NIPPON ZEON CO., LTD. (JP) | 1993-09-01 | — | — | EP | disclosed |
| US-4906768-A | Process for production of oxime derivatives | NIPPON ZEON CO., LTD. (JP) | 1990-03-06 | — | — | US | disclosed |
| EP-0194554-A2 | Process for production of oxime derivatives | NIPPON ZEON CO., LTD. (JP) | 1986-09-17 | — | — | EP | disclosed |