Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 10/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 9/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 7/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9815902 | 0.87 | RAD52 (0.41) | ADRA2AADRA2CADRA2BHTR1ANISCH | |
| SCHEMBL167589 | 0.82 | — | — | |
| Acetic Acid SCHEMBL11239341 | 0.81 | NISCH (0.43) | ADRA2AADRA2CADRA2BHTR1ANISCH | |
| SCHEMBL9210434 | 0.81 | RAD52 (0.44) | ADRA2AADRA2CNISCHRAD52KDM4E | |
| Phosphoric Acid SCHEMBL4317328 | 0.79 | ADRA2B (0.44) | ADRA2AADRA2CADRA2BHTR1ANISCH | |
| Propionic Acid SCHEMBL593943 | 0.78 | ADRA2B (0.42) | ADRA2AADRA2CADRA2BHTR1ANISCH | |
| SCHEMBL6251596 | 0.77 | RAD52 (0.48) | ADRA2AADRA2CNISCHRAD52ADRA1A | |
| Ethylenediamine SCHEMBL14335529 | 0.75 | ADRA2B (0.47) | ADRA2AADRA2CADRA2BHTR1ANISCH | |
| Alanine SCHEMBL3261340 | 0.75 | ADRA2B (0.40) | ADRA2AADRA2CADRA2BHTR1ANISCH | |
| SCHEMBL1995034 | 0.73 | ADRA2B (0.38) | ADRA2AADRA2CADRA2BHTR1ANISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517762-B1 | PROCESS FOR TREATMENT OF TEXTILES | NOVO NORDISK AS (DK) | 1993-12-08 | — | — | EP | disclosed |
| EP-0517762-A1 | PROCESS FOR TREATMENT OF TEXTILES. | NOVO NORDISK AS (DK) | 1992-12-16 | — | — | EP | disclosed |
| WO-1991013136-A1 | PROCESS FOR TREATMENT OF TEXTILES AND RINSING AGENT FOR USE IN THE PROCESS | NOVO NORDISK A/S (DK) | 1991-09-05 | — | — | WO | disclosed |