SCHEMBL9815902

SCHEMBL9815902

C=CCC1=NCCN1.CCOS(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 1/20 0.41
ADRA2C P18825 10/20 0.40
ADRA2A P08913 8/20 0.40
ADRA2B P18089 7/20 0.40
HTR1A P08908 3/20 0.40
NISCH Q9Y2I1 2/20 0.40
TAAR1 Q96RJ0 1/20 0.35
ADRA1A P35348 8/20 0.34
ADRA1D P25100 6/20 0.34
ADRA1B P35368 6/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
TSHR P16473 1/20 0.34
NFKB1 P19838 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
KCNH2 Q12809 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9560086 0.87 ADRA2A (0.43) RAD52ADRA2CADRA2AADRA2BHTR1A
SCHEMBL167589 0.78
Propionic Acid SCHEMBL593943 0.78 ADRA2B (0.42) ADRA2CADRA2AADRA2BHTR1ANISCH
Acetic Acid SCHEMBL11239341 0.77 NISCH (0.43) ADRA2CADRA2AADRA2BHTR1ANISCH
Phosphoric Acid SCHEMBL4317328 0.76 ADRA2B (0.44) RAD52ADRA2CADRA2AADRA2BHTR1A
Ethylenediamine SCHEMBL14335529 0.72 ADRA2B (0.47) ADRA2CADRA2AADRA2BHTR1ANISCH
Alanine SCHEMBL3261340 0.71 ADRA2B (0.40) ADRA2CADRA2AADRA2BHTR1ANISCH
SCHEMBL9210434 0.71 RAD52 (0.44) RAD52ADRA2CADRA2ANISCHTAAR1
SCHEMBL6362523 0.71 RAD52 (0.44) RAD52ADRA2CADRA2AADRA2BNISCH
SCHEMBL4193405 0.70 RAD52 (0.43) RAD52ADRA2CADRA2AADRA2BNISCH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0442965-A1 TOLUENE SULFONATE SALTS OF 2-ALKYL IMIDAZOLINES PPG INDUSTRIES, INC. (US) 1991-08-28 EP disclosed
US-5011937-A Internal and external antistatic agents for fibers PPG INDUSTRIES, INC. (US) 1991-04-30 US disclosed
US-4973616-A ANTISTATIC AGENTS FOR SYNTHETIC FIBERS AND PLASTICS PPG INDUSTRIES, INC. (US) 1990-11-27 US disclosed
WO-1990005724-A1 TOLUENE SULFONATE SALTS OF 2-ALKYL IMIDAZOLINES PPG INDUSTRIES, INC. (US) 1990-05-31 WO disclosed