Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559835 | 0.86 | MCL1 (0.46) | ALDH1A1KMT2AMEN1HSP90AB1MCL1 | |
| SCHEMBL21951012 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KMT2AMEN1HSP90AB1MCL1 | |
| SCHEMBL2257900 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1HSP90AB1MCL1 | |
| SCHEMBL31229283 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1HSP90AB1MCL1 | |
| SCHEMBL1557874 | 0.80 | MCL1 (0.59) | ALDH1A1KMT2AMEN1MCL1HPGD | |
| SCHEMBL9733974 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1HSP90AB1MCL1 | |
| SCHEMBL5678085 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1HSP90AB1MCL1 | |
| SCHEMBL9559750 | 0.78 | HSP90AB1 (0.48) | ALDH1A1KMT2AMEN1HSP90AB1MCL1 | |
| SCHEMBL11353652 | 0.77 | MCL1 (0.66) | ALDH1A1KMT2AMEN1HSP90AB1MCL1 | |
| SCHEMBL9043077 | 0.77 | HSP90AB1 (0.47) | ALDH1A1KMT2AMEN1HSP90AB1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103087009-A | Carboxylic acid derivative compound and preparation method and application thereof | SHANGSHAI SHYNDEC PHARMACEUTICAL CO LTD | 2013-05-08 | — | — | CN | disclosed |
| EP-0325247-B1 | CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-5061800-A | ANTITUMOR AGENTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0325247-A1 | Camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-07-26 | — | — | EP | disclosed |