Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713136 | 0.81 | ALDH1A1 (0.44) | ALDH1A1LMNACES2CES1CTSL | |
| SCHEMBL28879932 | 0.79 | ADRA2C (0.46) | ALDH1A1LMNAPKMATMMAOA | |
| SCHEMBL7778314 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNACES2CES1CTSL | |
| SCHEMBL8995282 | 0.77 | ALDH1A1 (0.41) | ALDH1A1LMNACES2CES1CTSL | |
| SCHEMBL9559836 | 0.75 | PARP1 (0.50) | ALDH1A1CTSLSMN1; SMN2HDAC8HDAC6 | |
| SCHEMBL11171647 | 0.74 | ALDH1A1 (0.42) | ALDH1A1LMNACES2CES1CTSL | |
| SCHEMBL16694617 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNACES2CES1SMN1; SMN2 | |
| SCHEMBL2631353 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNACES2CES1SMN1; SMN2 | |
| SCHEMBL28228323 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNACES2CES1SMN1; SMN2 | |
| SCHEMBL11186390 | 0.71 | ALDH1A1 (0.39) | ALDH1A1LMNACES2CES1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0325247-B1 | CAMPTOTHECIN DERIVATIVES AND PROCESS FOR PREPARING SAME | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1993-05-19 | — | — | EP | disclosed |
| US-5061800-A | ANTITUMOR AGENTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1991-10-29 | — | — | US | disclosed |
| EP-0325247-A1 | Camptothecin derivatives and process for preparing same | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 1989-07-26 | — | — | EP | disclosed |