Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TNF | P01375 | 2/20 | 0.31 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9512987 | 0.91 | STAT3 (0.39) | STAT3CNR1CNR2TYMSTOP1 | |
| SCHEMBL9569159 | 0.88 | STAT3 (0.41) | STAT3CNR1CNR2TYMSTOP1 | |
| SCHEMBL9560518 | 0.87 | STAT3 (0.37) | STAT3CNR1CNR2TYMSTOP1 | |
| SCHEMBL9560567 | 0.87 | STAT3 (0.37) | STAT3CNR1CNR2TYMSTOP1 | |
| SCHEMBL9510131 | 0.85 | TOP1 (0.36) | STAT3CNR1CNR2TYMSTOP1 | |
| SCHEMBL9569148 | 0.85 | STAT3 (0.38) | STAT3CNR1CNR2TYMSTOP1 | |
| SCHEMBL9560451 | 0.85 | STAT3 (0.36) | STAT3CNR1CNR2TYMSTOP1 | |
| SCHEMBL9560110 | 0.85 | SMN1; SMN2 (0.36) | STAT3CNR1CNR2TOP1KMT2A | |
| SCHEMBL9560596 | 0.84 | KDM4E (0.38) | STAT3CNR1CNR2TYMSTOP1 | |
| SCHEMBL9560529 | 0.84 | ALDH1A1 (0.38) | STAT3TYMSKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563732-A1 | 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |