Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 6/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510131 | 0.89 | TOP1 (0.36) | TYMSKMT2AMEN1STAT3MAPT | |
| SCHEMBL9560540 | 0.89 | TOP1 (0.36) | ALDH1A1TSHRFPR1KMT2AMEN1 | |
| SCHEMBL9560110 | 0.86 | SMN1; SMN2 (0.36) | ALDH1A1TSHRFPR1KMT2AMEN1 | |
| SCHEMBL9560451 | 0.85 | STAT3 (0.36) | TYMSKMT2AMEN1STAT3MAPT | |
| SCHEMBL9560538 | 0.84 | TOP1 (0.45) | ALDH1A1POLB | |
| SCHEMBL9560141 | 0.84 | STAT3 (0.39) | ALDH1A1TYMSKMT2AMEN1STAT3 | |
| SCHEMBL9560596 | 0.83 | KDM4E (0.38) | ALDH1A1TYMSALOX5KMT2AMEN1 | |
| SCHEMBL9512987 | 0.83 | STAT3 (0.39) | ALDH1A1TYMSKMT2AMEN1STAT3 | |
| SCHEMBL9569159 | 0.80 | STAT3 (0.41) | ALDH1A1TYMSKMT2AMEN1STAT3 | |
| SCHEMBL9560567 | 0.79 | STAT3 (0.37) | ALDH1A1TYMSKMT2AMEN1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563732-A1 | 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |