Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.63 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.63 |
| ▸ | CHEK2 | O96017 | 10/20 | 0.58 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | TOP1 | P11387 | 2/20 | 0.51 |
| ▸ | TOP2A | P11388 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560144 | 0.92 | KMT2A (0.54) | ALDH1A1SMN1; SMN2MEN1SLCO2B1GLA | |
| SCHEMBL5820715 | 0.79 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2MEN1SLCO2B1GLA | |
| Hydrochloric Acid SCHEMBL19460660 | 0.79 | TOP1 (0.74) | ALDH1A1SMN1; SMN2MEN1SLCO2B1GLA | |
| SCHEMBL29350649 | 0.78 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1SLCO2B1GLA | |
| SCHEMBL38686 | 0.78 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MEN1SLCO2B1GLA | |
| SCHEMBL23424053 | 0.78 | ALDH1A1 (0.80) | ALDH1A1SMN1; SMN2MEN1SLCO2B1GLA | |
| SCHEMBL6361354 | 0.77 | TOP1 (0.73) | ALDH1A1SMN1; SMN2MEN1SLCO2B1GLA | |
| Hydrochloric Acid SCHEMBL29387917 | 0.77 | ALDH1A1 (0.98) | ALDH1A1SMN1; SMN2MEN1SLCO2B1GLA | |
| SCHEMBL23424052 | 0.75 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MEN1SLCO2B1GLA | |
| SCHEMBL15969230 | 0.74 | ALDH1A1 (0.90) | ALDH1A1SMN1; SMN2MEN1SLCO2B1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5213979-A | Coculturing with epithelial cells from oviduct of bovines; increased milk production | W. R. GRACE & CO.-CONN. (US) | 1993-05-25 | — | — | US | disclosed |