Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 10/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 10/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24245843 | 0.89 | NR1H2 (0.56) | TSHRMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL3678693 | 0.77 | TSHR (0.61) | TSHRMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL131990 | 0.75 | NR1H2 (0.68) | NR1H2NR1H3MLYCDSMN1; SMN2 | |
| SCHEMBL13239428 | 0.75 | ALDH1A1 (0.57) | MAPK1MEN1KMT2ANR1H3 | |
| Water SCHEMBL1684070 | 0.73 | NR1H2 (0.65) | NR1H2NR1H3MLYCDSMN1; SMN2 | |
| SCHEMBL9561126 | 0.73 | TSHR (0.44) | TSHRMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL9561052 | 0.72 | NQO1 (0.47) | TSHRNR1H2NR1H3MLYCD | |
| SCHEMBL13758523 | 0.71 | NR1H2 (0.45) | NR1H2NR1H3MLYCD | |
| SCHEMBL17826 | 0.71 | MEN1 (0.60) | TSHRMAPK1HIF1AMEN1KMT2A | |
| SCHEMBL11458379 | 0.71 | TSHR (0.52) | TSHRMAPK1HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |