SCHEMBL3678693

SCHEMBL3678693

OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)C(F)(F)F

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.61
MAPK1 P28482 1/20 0.61
HIF1A Q16665 1/20 0.61
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
CYP19A1 P11511 10/20 0.46
LMNA P02545 1/20 0.42
CYP2A6 P11509 1/20 0.42
PDK1 Q15118 1/20 0.41
PDK2 Q15119 1/20 0.41
PDK3 Q15120 1/20 0.41
PDK4 Q16654 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
MIF P14174 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2860836 0.83 TSHR (0.74) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL2317622 0.82 TSHR (0.44) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL24245843 0.82 NR1H2 (0.56) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL5149151 0.80 ESR1 (0.45) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL3423025 0.80 PDK1 (0.55) KMT2APDK1PDK2PDK3PDK4
SCHEMBL17826 0.78 MEN1 (0.60) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL29091899 0.77 MEN1 (0.65) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL29092067 0.77 MEN1 (0.65) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL29091903 0.77 MEN1 (0.65) TSHRMAPK1HIF1AMEN1KMT2A
SCHEMBL9560285 0.77 TSHR (0.52) TSHRMAPK1HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116581374-B Gel polymer electrolyte capable of stably forming film, preparation method and application 中南大学 2025-04-29 CN claimed
CN-113343464-B Efficient tomato fruit sugar prediction improvement method based on fruit diameter nondestructive observation 中国农业大学 2024-09-13 CN claimed
US-20240304866-A1 Electrolyte Formulations for Optimal Performance in Si-Containing Lithium Ion Batteries ENEVATE CORP (US) 2024-09-12 US claimed
WO-2024143916-A1 ELECTROLYTE FOR LITHIUM SECONDARY BATTERY AND LITHIUM SECONDARY BATTERY COMPRISING SAME 에스케이온 주식회사 2024-07-04 WO claimed
CN-117451331-B Breaker mechanical characteristic monitoring device and method based on subsampled data 国网江苏省电力有限公司宿迁供电分公司 2024-06-18 CN claimed
US-11990585-B2 Electrolyte formulations for optimal performance in Si-containing lithium ion batteries ENEVATE CORPORATION (US) 2024-05-21 US claimed
US-20240079653-A1 Electrolyte Formulations for Optimal Performance in Si-Containing Lithium Ion Batteries ENEVATE CORPORATION 2024-03-07 US claimed
CN-117451331-A Breaker mechanical characteristic monitoring device and method based on subsampled data 国网江苏省电力有限公司宿迁供电分公司 2024-01-26 CN claimed
CN-117422904-A Image recognition method based on DCNN 江西理工大学 2024-01-19 CN claimed
CN-117335016-A High-voltage lithium ion battery 深圳新宙邦科技股份有限公司 2024-01-02 CN claimed
CN-116885100-A Negative electrode piece and secondary battery 广东省豪鹏新能源科技有限公司 2023-10-13 CN claimed
CN-116610925-B Prediction method for soil nitrogen accumulation in cow-corn circulating agriculture 吉林农业大学 2023-09-26 CN claimed
CN-116581374-A Gel polymer electrolyte capable of stably forming film, preparation method and application 中南大学 2023-08-11 CN claimed
CN-110799504-B Method for preparing 2, 5-dimethyl furandicarboxylate from hydroxymethyl furfural 韩国生产技术研究院 2023-05-30 CN claimed
CN-113451541-B High-voltage lithium ion positive electrode piece, battery and manufacturing method thereof 上海空间电源研究所 2023-02-03 CN claimed
CN-114824447-A Sodium battery and preparation method thereof 深圳市超壹新能源科技有限公司 2022-07-29 CN claimed
US-11233272-B2 Zero flammability electrolyte for lithium-ion cell NIO USA, INC. (US) 2022-01-25 US claimed
US-7087789-B2 Methods for nucleophilic fluoromethylation UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2006-08-08 US claimed
US-20040230079-A1 Methods for nucleophilic fluoromethylation SOUTHERN CALIFORNIA, UNIVERSITY OF 2004-11-18 US claimed
WO-2004063129-A2 METHODS FOR NUCLEOPHILIC FLUOROMETHYLATION UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2004-07-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040230079-A1 Methods for nucleophilic fluoromethylation PHF2, HAO2, GSTM2 TSHR 2421/4885MAPK1 3505/4885HIF1A 3433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.