Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 6/20 | 0.33 |
| ▸ | RAB9A | P51151 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1984960 | 0.83 | DPP4 (0.34) | DPP4NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL20535309 | 0.82 | DPP4 (0.37) | DPP4NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL28351417 | 0.79 | DPP4 (0.32) | DPP4NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL25361497 | 0.77 | DPP4 (0.31) | DPP4NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL14958040 | 0.76 | RPS6KB2 (0.35) | DPP4NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL12441750 | 0.71 | KDM4E (0.33) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL19874953 | 0.68 | CYP1A2 (0.31) | KMT2AMEN1 | |
| SCHEMBL20550992 | 0.67 | FBP1 (0.36) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL2290788 | 0.67 | FBP1 (0.36) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL2341397 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5255484-A | — | — | None | — | — | JP | disclosed |
| EP-2644627-B1 | CATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING THIENYL-SUBSTITUTED SILANES | PETROCHINA CO LTD (CN) | 2017-01-11 | — | — | EP | disclosed |
| EP-2644627-A1 | CATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING THIENYL-SUBSTITUTED SILANES | Petrochina Company Limited (CN) | 2013-10-02 | — | — | EP | disclosed |
| US-8541332-B2 | Catalyst for polymerization of olefins comprising thienyl-substituted silanes | PETROCHINA COMPANY LIMITED (CN) | 2013-09-24 | — | — | US | disclosed |
| US-20130131292-A1 | CATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING THIENYL-SUBSTITUTED SILANES | PETROCHINA COMPANY LIMITED (CN) | 2013-05-23 | — | — | US | disclosed |
| JP-H05255484-A | DIALKOXY-BIS(2-THIENYL)SILANE POLYMER AND ITS PRODUCTION | AGENCY OF IND SCIENCE & TECHNOL | 1993-10-05 | — | — | JP | disclosed |