Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560348 | 0.82 | DPP4 (0.34) | DPP4RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL1984960 | 0.82 | DPP4 (0.34) | DPP4RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL4351074 | 0.79 | TDO2 (0.33) | DPP4RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL28351417 | 0.77 | DPP4 (0.32) | DPP4RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL25361497 | 0.76 | DPP4 (0.31) | DPP4RAB9AKDM4EALDH1A1NPC1 | |
| SCHEMBL2290788 | 0.71 | FBP1 (0.36) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL2341397 | 0.71 | — | — | |
| SCHEMBL20550992 | 0.71 | FBP1 (0.36) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL12441750 | 0.70 | KDM4E (0.33) | RAB9AKDM4EALDH1A1NPC1HPGD | |
| SCHEMBL27916841 | 0.69 | FBP1 (0.35) | RAB9AKDM4EALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520434-B | Method for preparing arylalkoxysilanes by dehydrogenative silylation | 美国陶氏有机硅公司 | 2022-08-23 | — | — | CN | claimed |
| EP-3609900-B1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORP (US) | 2021-02-17 | — | — | EP | claimed |
| US-20200123181-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORP (US) | 2020-04-23 | — | — | US | claimed |
| EP-3609900-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | Dow Silicones Corporation (US) | 2020-02-19 | — | — | EP | claimed |
| WO-2018190999-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORPORATION (US) | 2018-10-18 | — | — | WO | claimed |
| CN-110520434-B | Method for preparing arylalkoxysilanes by dehydrogenative silylation | 美国陶氏有机硅公司 | 2022-08-23 | — | — | CN | disclosed |
| EP-3609900-B1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORP (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20200123181-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORP (US) | 2020-04-23 | — | — | US | disclosed |
| EP-3609900-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | Dow Silicones Corporation (US) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018190999-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DOW SILICONES CORPORATION (US) | 2018-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123181-A1 | METHOD FOR PREPARING ARYLALKOXYSILANES BY DEHYDROGENATIVE SILYLATION | DHPS, ALK, BCR | DPP4 3346/4885RAB9A 138/4885KDM4E 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.