Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 6/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560364 | 0.86 | TOP1 (0.38) | TOP1TOP2ATOP2B | |
| SCHEMBL9509708 | 0.85 | TOP1 (0.52) | TOP1KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL9560276 | 0.82 | TOP2A (0.57) | TOP1KDM4EALDH1A1POLBTOP2A | |
| SCHEMBL9560755 | 0.81 | KDM4E (0.47) | TOP1KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL9569188 | 0.81 | TOP1 (0.41) | TOP1KDM4EALDH1A1POLBHSP90AA1 | |
| SCHEMBL9509558 | 0.80 | TOP1 (0.52) | TOP1KDM4EALDH1A1POLBHSP90AA1 | |
| SCHEMBL9560567 | 0.79 | STAT3 (0.37) | TOP1KDM4EKMT2AALDH1A1TOP2A | |
| SCHEMBL9569194 | 0.79 | TOP1 (0.51) | TOP1KDM4EKMT2AALDH1A1POLB | |
| SCHEMBL9560791 | 0.79 | KDM4E (0.59) | TOP1KDM4EALDH1A1POLBTOP2A | |
| SCHEMBL9560538 | 0.74 | TOP1 (0.45) | TOP1KDM4EALDH1A1POLBTOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563732-A1 | 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |