Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 5/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560540 | 0.90 | TOP1 (0.36) | TOP1GPR35KDM4EALDH1A1GAA | |
| SCHEMBL9509558 | 0.85 | TOP1 (0.52) | TOP1KDM4EPOLBTOP2ATOP2B | |
| SCHEMBL9560529 | 0.84 | ALDH1A1 (0.38) | POLBALDH1A1 | |
| SCHEMBL9509708 | 0.77 | TOP1 (0.52) | TOP1KDM4EPOLBTOP2ATOP2B | |
| SCHEMBL10538537 | 0.76 | STAT3 (0.47) | TOP1KDM4EALDH1A1 | |
| SCHEMBL9509563 | 0.76 | TOP1 (0.40) | TOP1KDM4EPOLBTOP2ATOP2B | |
| SCHEMBL9560362 | 0.74 | TOP1 (0.49) | TOP1KDM4EPOLBTOP2ATOP2B | |
| SCHEMBL9510131 | 0.73 | TOP1 (0.36) | TOP1KDM4E | |
| SCHEMBL10518098 | 0.72 | KDM4E (0.49) | GPR35KDM4EPOLBTOP2ATOP2B | |
| SCHEMBL9569194 | 0.72 | TOP1 (0.51) | TOP1KDM4EPOLBTOP2ATOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563732-A1 | 7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazinecarboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |