SCHEMBL9560384

SCHEMBL9560384

NC(=O)C(O)C(O)C(=O)c1cccc(N)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.50
F2 P00734 1/20 0.47
PLG P00747 1/20 0.47
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
LMNA P02545 2/20 0.44
NPC1 O15118 1/20 0.44
MITF O75030 1/20 0.44
POLB P06746 1/20 0.44
KDM4C Q9H3R0 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ADRB2 P07550 2/20 0.40
ADRB1 P08588 2/20 0.40
ADRB3 P13945 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CPN1 P15169 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21200752 0.76 ACHE (0.56) PBRM1F2PLGPRSS1PRSS2
SCHEMBL9254112 0.76 PBRM1 (0.55) PBRM1F2PLGPRSS1PRSS2
3-Aminobenzamide SCHEMBL27679552 0.74 PBRM1 (0.63) PBRM1F2PLGPRSS1PRSS2
3-Aminobenzamide SCHEMBL16070 0.74 PBRM1 (0.63) PBRM1F2PLGPRSS1PRSS2
SCHEMBL9041395 0.74 PBRM1 (0.53) PBRM1F2PLGPRSS1PRSS2
SCHEMBL6755743 0.74 CES2 (0.67) PBRM1F2PLGPRSS1PRSS2
3-Aminobenzamide SCHEMBL8688920 0.72 F2 (0.63) PBRM1F2PLGPRSS1PRSS2
3-Aminobenzamide SCHEMBL28944114 0.72 PBRM1 (0.61) PBRM1F2PLGPRSS1PRSS2
3-Aminobenzamide SCHEMBL28015741 0.72 PBRM1 (0.61) PBRM1F2PLGPRSS1PRSS2
SCHEMBL11586994 0.72 PBRM1 (0.51) PBRM1F2PLGPRSS1PRSS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5257310-A None JP disclosed
JP-H05257310-A ELECTROPHOTOGRAPHIC SENSITIVE BODY FUJI XEROX CO LTD 1993-10-08 JP disclosed