Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478458 | 0.87 | MAOB (0.53) | LTA4HTTRLMNATSHRMAOB | |
| SCHEMBL29661187 | 0.85 | LTA4H (0.67) | LTA4HTTRTSHRHSD17B10MAOB | |
| SCHEMBL358425 | 0.85 | LTA4H (0.67) | LTA4HTTRTSHRHSD17B10MAOB | |
| SCHEMBL30979265 | 0.84 | LTA4H (0.55) | LTA4HTTRLMNATSHRSMN1; SMN2 | |
| SCHEMBL5112767 | 0.84 | LTA4H (0.55) | LTA4HTTRLMNATSHRSMN1; SMN2 | |
| SCHEMBL9560821 | 0.84 | MAPT (0.44) | MAPTTSHRHSD17B10MAOBSMN1; SMN2 | |
| Methane SCHEMBL10579323 | 0.83 | LTA4H (0.64) | LTA4HTTRTSHRHSD17B10MAOB | |
| SCHEMBL1746839 | 0.82 | FFAR1 (0.53) | LTA4HTTRTSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL1681007 | 0.82 | SMN1; SMN2 (0.60) | LTA4HSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL2351004 | 0.82 | LTA4H (0.53) | LTA4HTTRLMNATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4423243-A | Process for the preparation of 2,2-dimethyl-3-vinyl-cyclopropanecarboxylic acids and esters | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | claimed |
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |
| US-4532258-A | Controlling insects, mites, pests | KURARAY CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
| US-4440955-A | Process for the preparation of 2,2-dimethyl-3-vinyl-cyclopropanecarboxylic acids and esters | BAYER AKTIENGESELLSCHAFT (DE) | 1984-04-03 | — | — | US | disclosed |
| US-4423243-A | Process for the preparation of 2,2-dimethyl-3-vinyl-cyclopropanecarboxylic acids and esters | BAYER AKTIENGESELLSCHAFT (DE) | 1983-12-27 | — | — | US | disclosed |
| EP-0008340-B1 | FLUOROALKENYL-SUBSTITUTED CYCLOPROPANECARBOXYLIC ACID ESTERS, INTERMEDIATE PRODUCTS THEREFOR, PREPARATION OF THE COMPOUNDS AND THEIR UTILIZATION AS INSECTICIDES AND/OR ACARICIDES | BAYER AG (DE) | 1983-12-21 | — | — | EP | disclosed |
| US-4405639-A | INSECTICIDES; PESTICIDES; MITICIDES; NEMATOCIDES; PARACITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-09-20 | — | — | US | disclosed |
| US-4390547-A | 2,2-Dimethyl-3-(substituted ethyl)cyclopropane carboxylate pesticidal compositions and methods | KURARAY CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4348323-A | FLUORINE-CONTAINING BENZODIOXINE INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |
| EP-0056154-A1 | Process for the preparation of 2,2-dimethyl-3-vinyl-cyclopropane-carboxylic acids and their esters | BAYER AG (DE) | 1982-07-21 | — | — | EP | disclosed |
| US-4299839-A | Novel pesticides and pesticidal compositions cyclopropanecarboxylates and pesticidal method | KURARAY CO., LTD. (JP) | 1981-11-10 | — | — | US | disclosed |
| US-4284643-A | Combating arthropods with novel fluorine-containing phenylacetic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| US-4252820-A | Arthropodicidal 2,2-dimethyl-3-(2-perfluoroalkyl-2-perhaloalkyl-vinyl)-cyclopropanecarboxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
| US-4242357-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |
| EP-0008732-A2 | Fluorine-containing esters of phenylacetic acids, process for their preparation and their use as insecticides and acaricides; intermediate products for their preparation | BAYER AG (DE) | 1980-03-19 | — | — | EP | disclosed |
| EP-0008340-A1 | Fluoroalkenyl-substituted cyclopropanecarboxylic acid esters, intermediate products therefor, preparation of the compounds and their utilization as insecticides and/or acaricides | BAYER AG (DE) | 1980-03-05 | — | — | EP | disclosed |