Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560308 | 0.91 | MAPT (0.43) | LMNAPOLBMAPTNPSR1MEN1 | |
| SCHEMBL9560239 | 0.87 | RARB (0.53) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL1496818 | 0.86 | NPSR1 (0.51) | LMNAPOLBMAPTNPSR1MEN1 | |
| SCHEMBL9560789 | 0.86 | RARB (0.54) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL9560471 | 0.85 | NPSR1 (0.41) | LMNAPOLBMAPTNPSR1MEN1 | |
| SCHEMBL9559969 | 0.85 | SMN1; SMN2 (0.57) | LMNAPOLBMAPTNPSR1MEN1 | |
| SCHEMBL9560983 | 0.85 | GAA (0.49) | LMNAMAPTNPSR1MEN1KMT2A | |
| SCHEMBL9560346 | 0.84 | POLB (0.45) | LMNAPOLBMAPTMEN1KMT2A | |
| SCHEMBL9560612 | 0.83 | RARB (0.51) | LMNAPOLBMAPTNPSR1MEN1 | |
| SCHEMBL9560963 | 0.82 | MAPT (0.50) | LMNAPOLBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190688-A | Perfluoroalkyl Compounds Dopes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0300009-B1 | LIQUID CRYSTALLINE MIXTURE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |