Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560239 | 0.91 | RARB (0.53) | MAPTMEN1KMT2ARARBALDH1A1 | |
| SCHEMBL9560760 | 0.91 | LMNA (0.49) | MAPTNPSR1MEN1KMT2ALMNA | |
| SCHEMBL9560789 | 0.90 | RARB (0.54) | MAPTMEN1KMT2ARARBALDH1A1 | |
| SCHEMBL9560846 | 0.87 | RARB (0.45) | MAPTNPSR1MEN1KMT2ARARB | |
| SCHEMBL9560428 | 0.86 | SMN1; SMN2 (0.58) | MAPTL3MBTL1KDM4EALDH1A1THRB | |
| SCHEMBL9560511 | 0.85 | MAPT (0.41) | MAPTMEN1KMT2ARARBLMNA | |
| SCHEMBL9560341 | 0.83 | MAPT (0.47) | MAPTMEN1KMT2ARARBLMNA | |
| SCHEMBL9560410 | 0.83 | MAPT (0.47) | MAPTMEN1KMT2ARARBLMNA | |
| SCHEMBL9560959 | 0.83 | MAPT (0.47) | MAPTMEN1KMT2ARARBLMNA | |
| SCHEMBL1496818 | 0.83 | NPSR1 (0.51) | MAPTNPSR1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190688-A | Perfluoroalkyl Compounds Dopes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0300009-B1 | LIQUID CRYSTALLINE MIXTURE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |