Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.53 |
| ▸ | RARA | P10276 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | THRA | P10827 | 6/20 | 0.44 |
| ▸ | THRB | P10828 | 6/20 | 0.44 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560789 | 0.99 | RARB (0.54) | RARBRARAMEN1KMT2AALDH1A1 | |
| SCHEMBL9560308 | 0.91 | MAPT (0.43) | RARBRARAMEN1KMT2AALDH1A1 | |
| SCHEMBL9560984 | 0.88 | RARB (0.57) | RARBRARAMEN1KMT2AALDH1A1 | |
| SCHEMBL9560760 | 0.87 | LMNA (0.49) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9560499 | 0.87 | SMN1; SMN2 (0.60) | RARBALDH1A1MAPTTHRB | |
| SCHEMBL9560572 | 0.87 | RARB (0.59) | RARBRARAMEN1KMT2AALDH1A1 | |
| SCHEMBL9560781 | 0.87 | RARB (0.59) | RARBRARAMEN1KMT2AALDH1A1 | |
| SCHEMBL9560468 | 0.86 | RARB (0.49) | RARBRARAMEN1KMT2AALDH1A1 | |
| SCHEMBL9560527 | 0.86 | SMN1; SMN2 (0.59) | RARBALDH1A1MAPTTHRB | |
| SCHEMBL9560589 | 0.86 | SMN1; SMN2 (0.59) | RARBALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190688-A | Perfluoroalkyl Compounds Dopes | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-03-02 | — | — | US | disclosed |
| EP-0300009-B1 | LIQUID CRYSTALLINE MIXTURE | MERCK PATENT GmbH (DE) | 1992-01-02 | — | — | EP | disclosed |