Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 17/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 17/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560084 | 0.89 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1 | |
| SCHEMBL9561574 | 0.84 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9560768 | 0.80 | CYSLTR2 (0.53) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560196 | 0.77 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9560080 | 0.77 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9560183 | 0.77 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9559903 | 0.77 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9560033 | 0.76 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARG | |
| SCHEMBL9485959 | 0.75 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560005 | 0.75 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5189226-A | Chemical intermediate for diacid | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-23 | — | — | US | disclosed |
| US-4937253-A | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-06-26 | — | — | US | disclosed |