Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 14/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561682 | 0.92 | CETP (0.40) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL9560683 | 0.91 | KDM4E (0.50) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL9570794 | 0.90 | FFAR1 (0.44) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL7930457 | 0.89 | CETP (0.45) | CETPFFAR1FFAR4 | |
| SCHEMBL9560903 | 0.88 | FFAR1 (0.46) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL9570765 | 0.87 | CETP (0.44) | CETPFFAR1FFAR4 | |
| SCHEMBL9570907 | 0.86 | FAAH (0.42) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL9570580 | 0.86 | CETP (0.49) | KDM4EALDH1A1HTTSMN1; SMN2CETP | |
| SCHEMBL409247 | 0.86 | FFAR1 (0.51) | SMN1; SMN2CETPFFAR1FFAR4 | |
| SCHEMBL9561406 | 0.86 | FFAR1 (0.51) | SMN1; SMN2CETPFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |