Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.68 |
| ▸ | TAS1R3 | Q7RTX0 | 14/20 | 0.63 |
| ▸ | TAS1R1 | Q7RTX1 | 13/20 | 0.63 |
| ▸ | TAS1R2 | Q8TE23 | 12/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517994 | 0.92 | MLYCD (0.77) | MLYCDTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL517895 | 0.87 | MLYCD (0.71) | MLYCDTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL13927734 | 0.86 | TAS1R3 (0.72) | MLYCDTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL13927736 | 0.86 | TAS1R3 (0.72) | MLYCDTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL4175029 | 0.86 | TAS1R3 (0.72) | MLYCDTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL889072 | 0.84 | MLYCD (0.68) | MLYCDTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL20712985 | 0.84 | MLYCD (0.67) | MLYCDTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL9691775 | 0.84 | MLYCD (0.67) | MLYCDTAS1R3TAS1R1TAS1R2ALDH1A1 | |
| SCHEMBL2453198 | 0.82 | TAS1R3 (0.81) | MLYCDTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL889027 | 0.81 | MLYCD (0.63) | MLYCDTAS1R3TAS1R1TAS1R2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362252-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| EP-1797082-B1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2010-10-14 | — | — | US | disclosed |
| US-7777038-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-08-17 | — | — | US | disclosed |
| US-20090326008-A1 | NF-kappa B Inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2043644-A1 | NF- B INHIBITOR | Otsuka Pharmaceutical Co., Ltd. (JP) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2008010601-A1 | NF- ϰB INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |
| US-20070179173-A1 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326008-A1 | NF-kappa B Inhibitor | NFKBIA, NFKB2, IKBKB | MLYCD 4635/4885TAS1R3 4333/4885TAS1R1 3856/4885 |
| US-20070179173-A1 | Carbostyril compound | GTF2F1, F3, GTF2F2 | MLYCD 3616/4885TAS1R3 484/4885TAS1R1 151/4885 |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | GTF2F1, F3, GTF2F2 | MLYCD 3616/4885TAS1R3 484/4885TAS1R1 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.