Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560951 | 0.90 | L3MBTL1 (0.35) | SMN1; SMN2SLC6A4TACR1TTR | |
| SCHEMBL9560800 | 0.87 | SMN1; SMN2 (0.35) | SMN1; SMN2SLC6A4TACR1TTRFFAR4 | |
| SCHEMBL10835390 | 0.86 | TACR1 (0.36) | SMN1; SMN2SLC6A4TACR1TTRMAOB | |
| SCHEMBL9560514 | 0.86 | MAPT (0.41) | SMN1; SMN2SLC6A4TACR1 | |
| SCHEMBL10751071 | 0.82 | SMN1; SMN2 (0.33) | SMN1; SMN2SLC6A4TACR1TTRMAOB | |
| SCHEMBL10836116 | 0.79 | TACR1 (0.35) | SLC6A4TACR1TTRFFAR4LPAR1 | |
| SCHEMBL9558410 | 0.78 | TACR1 (0.44) | SLC6A4TACR1TTRMAOBLPAR1 | |
| SCHEMBL10837117 | 0.78 | NPC1 (0.38) | TACR1TTRFFAR4LPAR1LPAR5 | |
| SCHEMBL10835835 | 0.78 | TACR1 (0.34) | SLC6A4TACR1TTRFFAR4LPAR1 | |
| SCHEMBL10835913 | 0.78 | TACR1 (0.34) | SLC6A4TACR1TTRFFAR4LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |