Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560585 | 0.91 | MAPK14 (0.39) | SMN1; SMN2MAPK14TACR1MRGPRX4 | |
| SCHEMBL9560403 | 0.91 | NR3C2 (0.37) | SMN1; SMN2CHRM3TTRNR3C2LPAR1 | |
| SCHEMBL9560709 | 0.90 | L3MBTL1 (0.36) | SMN1; SMN2CHRM3TTRSLC6A4MRGPRX4 | |
| SCHEMBL9560793 | 0.89 | NR4A1 (0.36) | CHRM3TTRFFAR4NR3C2LPAR1 | |
| SCHEMBL9560878 | 0.88 | LMNA (0.41) | SMN1; SMN2CHRM3TTRNR3C2LPAR1 | |
| SCHEMBL9561340 | 0.88 | LTA4H (0.38) | FFAR4SLC6A4MAPK14TACR1AR | |
| SCHEMBL9560474 | 0.88 | MAPT (0.39) | SMN1; SMN2SLC6A4POLB | |
| SCHEMBL9560338 | 0.88 | ALOX5 (0.33) | NR3C2LPAR1LPAR5TACR1POLB | |
| SCHEMBL9561247 | 0.87 | SMN1; SMN2 (0.34) | SMN1; SMN2TTRFFAR4SLC6A4LPAR1 | |
| SCHEMBL9560512 | 0.87 | LMNA (0.40) | SMN1; SMN2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |