Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77341 | 0.91 | CHRNB2 (0.66) | CHRNB2CHRNA4KMT2AALDH1A1MEN1 | |
| SCHEMBL15498199 | 0.87 | CHRNB2 (0.73) | CHRNB2CHRNA4KMT2AALDH1A1MEN1 | |
| SCHEMBL29832812 | 0.86 | CHRNB2 (0.64) | CHRNB2CHRNA4KMT2AALDH1A1MEN1 | |
| SCHEMBL5523744 | 0.86 | CHRNB2 (0.64) | CHRNB2CHRNA4KMT2AALDH1A1MEN1 | |
| SCHEMBL15720996 | 0.85 | CHRNB2 (0.63) | CHRNB2CHRNA4KMT2AALDH1A1MEN1 | |
| SCHEMBL5518334 | 0.85 | CHRNB2 (0.62) | CHRNB2CHRNA4KMT2AALDH1A1MEN1 | |
| SCHEMBL31087898 | 0.85 | CHRNB2 (0.62) | CHRNB2CHRNA4KMT2AALDH1A1MEN1 | |
| SCHEMBL8955653 | 0.84 | CHRNB2 (0.61) | CHRNB2CHRNA4KMT2AALDH1A1MEN1 | |
| SCHEMBL31087905 | 0.84 | CHRNB2 (0.61) | CHRNB2CHRNA4KMT2AALDH1A1MEN1 | |
| SCHEMBL31087900 | 0.84 | CHRNB2 (0.61) | CHRNB2CHRNA4KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732063-B2 | Kinase inhibitors | RESPIVERT LIMITED (GB) | 2017-08-15 | — | — | US | disclosed |
| EP-2925742-B1 | KINASE INHIBITORS | RESPIVERT LTD (GB) | 2016-10-26 | — | — | EP | disclosed |
| US-20150329523-A1 | KINASE INHIBITORS | OXULAR ACQUISITIONS LIMITED (GB) | 2015-11-19 | — | — | US | disclosed |
| EP-2925742-A1 | KINASE INHIBITORS | Respivert Limited (GB) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014076484-A1 | KINASE INHIBITORS | RESPIVERT LIMITED (GB) | 2014-05-22 | — | — | WO | disclosed |
| US-5243004-A | Polymeric conductors | FUJI PHOTO FILM CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329523-A1 | KINASE INHIBITORS | SYK, SRC, BTK | CHRNB2 2178/4885CHRNA4 3163/4885KMT2A 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.