Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL842249 | 0.87 | NPC1 (0.48) | NPC1RAB9ACASP1LMNANPSR1 | |
| SCHEMBL8391733 | 0.82 | NPC1 (0.54) | NPC1RAB9ACASP1TP53SMN1; SMN2 | |
| SCHEMBL9127262 | 0.82 | SMN1; SMN2 (0.47) | NPC1RAB9ACASP1LMNANPSR1 | |
| SCHEMBL9125291 | 0.79 | SMN1; SMN2 (0.44) | NPC1RAB9ACASP1LMNANPSR1 | |
| SCHEMBL8238907 | 0.79 | PKM (0.58) | NPC1RAB9ACASP1LMNANPSR1 | |
| SCHEMBL9126182 | 0.78 | GSK3B (0.39) | NPC1RAB9ACASP1LMNANPSR1 | |
| SCHEMBL10360192 | 0.78 | NPC1 (0.51) | NPC1RAB9ACASP1LMNANPSR1 | |
| SCHEMBL9124444 | 0.78 | NPC1 (0.49) | NPC1RAB9ACASP1LMNANPSR1 | |
| SCHEMBL764568 | 0.77 | SMN1; SMN2 (0.53) | NPC1RAB9ACASP1LMNANPSR1 | |
| SCHEMBL5623097 | 0.77 | NPC1 (0.68) | NPC1RAB9ALMNANPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270281-A | Chromogenic compound | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-12-14 | — | — | US | disclosed |