Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.64 |
| ▸ | CA2 | P00918 | 5/20 | 0.64 |
| ▸ | CA12 | O43570 | 4/20 | 0.64 |
| ▸ | CA7 | P43166 | 4/20 | 0.64 |
| ▸ | CA9 | Q16790 | 4/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.64 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 4/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.53 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL868290 | 0.92 | LMNA (0.62) | CA1CA2CA12CA7CA9 | |
| SCHEMBL334524 | 0.91 | CA12 (0.77) | CA1CA2CA12CA7CA9 | |
| SCHEMBL2708353 | 0.84 | CA1 (0.72) | CA1CA2CA12CA7CA9 | |
| SCHEMBL31890210 | 0.84 | CA1 (0.72) | CA1CA2CA12CA7CA9 | |
| SCHEMBL6471721 | 0.84 | CA1 (0.72) | CA1CA2CA12CA7CA9 | |
| Hydrochloric Acid SCHEMBL14128574 | 0.83 | CA1 (0.70) | CA1CA2CA12CA7CA9 | |
| SCHEMBL3429430 | 0.82 | CYP1A2 (0.49) | CA1CA2CA12CA7CA9 | |
| SCHEMBL940578 | 0.80 | LMNA (0.65) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30582428 | 0.80 | LMNA (0.65) | CA1CA2CA12CA7CA9 | |
| SCHEMBL3523526 | 0.80 | LMNA (0.64) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5231113-A | Skin disorders, immunology or wound healing agents | ALLERGAN, INC. (US) | 1993-07-27 | — | — | US | disclosed |