Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.31 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.30 |
| ▸ | FNTB | P49356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598780 | 0.86 | CPB2 (0.34) | ANPEPRNPEPDNPEPSLC7A5 | |
| Histidine SCHEMBL28237926 | 0.82 | SLC7A5 (0.40) | ANPEPRNPEPDNPEPSLC7A5FNTA | |
| SCHEMBL28101256 | 0.81 | ANPEP (0.33) | ANPEPRNPEPDNPEPSLC7A5 | |
| SCHEMBL3750901 | 0.81 | ANPEP (0.31) | ANPEPRNPEPDNPEPSLC7A5 | |
| SCHEMBL27691471 | 0.80 | ANPEP (0.44) | ANPEPRNPEPDNPEPSLC7A5 | |
| Histidine SCHEMBL342891 | 0.78 | CYP3A4 (0.40) | RNPEPSLC7A5 | |
| Histidine SCHEMBL27681989 | 0.78 | CYP3A4 (0.40) | RNPEPSLC7A5 | |
| Histidine SCHEMBL342892 | 0.78 | CYP3A4 (0.40) | RNPEPSLC7A5 | |
| SCHEMBL1959818 | 0.78 | CPB2 (0.33) | — | |
| Histidine SCHEMBL28650960 | 0.77 | CYP3A4 (0.40) | RNPEPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346460-B1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION (IT) | 1993-03-10 | — | — | EP | disclosed |
| US-5110798-A | Immunomodulators for bone marrow transplants | CO PHARMA CORPORATION S.R.L. (IT) | 1992-05-05 | — | — | US | disclosed |
| EP-0346460-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION. | CO PHARMA CORP SRL (IT) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989005818-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION S.R.L. (IT) | 1989-06-29 | — | — | WO | disclosed |