Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 16/20 | 0.41 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | FPGS | Q05932 | 1/20 | 0.35 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561734 | 1.00 | HPRT1 (0.41) | HPRT1PNPPRMT5CARM1PRMT1 | |
| SCHEMBL9561455 | 0.96 | HPRT1 (0.41) | HPRT1PNPCPB1CPB2 | |
| SCHEMBL9561054 | 0.96 | HPRT1 (0.41) | HPRT1PNPCPB1CPB2 | |
| SCHEMBL9561407 | 0.91 | HPRT1 (0.39) | HPRT1PNP | |
| SCHEMBL9561486 | 0.86 | PRMT5 (0.39) | PRMT5CARM1PRMT1WDR77PRMT7 | |
| SCHEMBL9561744 | 0.86 | PRMT5 (0.39) | PRMT5CARM1PRMT1WDR77PRMT7 | |
| SCHEMBL10534207 | 0.85 | HPRT1 (0.39) | HPRT1PNPCPB1CPB2 | |
| SCHEMBL9561462 | 0.83 | CPB1 (0.40) | PRMT5CARM1PRMT1WDR77PRMT7 | |
| SCHEMBL9561069 | 0.83 | CPB1 (0.40) | PRMT5CARM1PRMT1WDR77PRMT7 | |
| SCHEMBL9561414 | 0.78 | NPY4R (0.40) | PRMT5CARM1PRMT1WDR77PRMT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346460-B1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION (IT) | 1993-03-10 | — | — | EP | claimed |
| EP-0346460-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION. | CO PHARMA CORP SRL (IT) | 1989-12-20 | — | — | EP | claimed |
| WO-1989005818-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION S.R.L. (IT) | 1989-06-29 | — | — | WO | claimed |
| EP-0346460-B1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION (IT) | 1993-03-10 | — | — | EP | disclosed |
| EP-0346460-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION. | CO PHARMA CORP SRL (IT) | 1989-12-20 | — | — | EP | disclosed |
| WO-1989005818-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION S.R.L. (IT) | 1989-06-29 | — | — | WO | disclosed |