Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 8/20 | 0.35 |
| ▸ | ADCY5 | O95622 | 3/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | NRP1 | O14786 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561462 | 1.00 | CPB1 (0.40) | CPB1CPB2PRMT5CARM1PRMT1 | |
| SCHEMBL9561486 | 0.96 | PRMT5 (0.39) | CPB1CPB2PRMT5CARM1PRMT1 | |
| SCHEMBL9561744 | 0.96 | PRMT5 (0.39) | CPB1CPB2PRMT5CARM1PRMT1 | |
| SCHEMBL9561414 | 0.92 | NPY4R (0.40) | CPB1CPB2PRMT5CARM1PRMT1 | |
| SCHEMBL9561455 | 0.87 | HPRT1 (0.41) | CPB1CPB2 | |
| SCHEMBL9561054 | 0.87 | HPRT1 (0.41) | CPB1CPB2 | |
| SCHEMBL10534213 | 0.86 | NPY4R (0.36) | CPB1CPB2PRMT5CARM1PRMT1 | |
| SCHEMBL9561734 | 0.83 | HPRT1 (0.41) | CPB1CPB2PRMT5CARM1PRMT1 | |
| SCHEMBL9561473 | 0.83 | HPRT1 (0.41) | CPB1CPB2PRMT5CARM1PRMT1 | |
| SCHEMBL10532501 | 0.83 | ADCY5 (0.37) | PRMT5CARM1PRMT1WDR77PRMT7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346460-B1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION (IT) | 1993-03-10 | — | — | EP | claimed |
| EP-0346460-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION. | CO PHARMA CORP SRL (IT) | 1989-12-20 | — | — | EP | claimed |
| WO-1989005818-A1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION S.R.L. (IT) | 1989-06-29 | — | — | WO | claimed |
| EP-0346460-B1 | PURINE DERIVATIVES HAVING PHARMACOLOGICAL ACTION | CO PHARMA CORPORATION (IT) | 1993-03-10 | — | — | EP | disclosed |