Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 2/20 | 0.30 |
| ▸ | F10 | P00742 | 2/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.30 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560861 | 0.84 | KCNH2 (0.37) | KCNH2LOXLOXL2F2F10 | |
| SCHEMBL10361286 | 0.82 | KCNH2 (0.44) | KCNH2LOXLOXL2F2F10 | |
| SCHEMBL27690318 | 0.77 | KCNH2 (0.53) | KCNH2LOXL2F2F10PRSS1 | |
| SCHEMBL6856754 | 0.77 | KCNH2 (0.44) | KCNH2LOXLOXL2F2F10 | |
| SCHEMBL9682557 | 0.75 | KCNH2 (0.40) | KCNH2LOXLOXL2F2F10 | |
| SCHEMBL9519808 | 0.75 | KCNH2 (0.40) | KCNH2LOXLOXL2F2F10 | |
| SCHEMBL9560684 | 0.75 | LTA4H (0.40) | KCNH2 | |
| SCHEMBL9561348 | 0.74 | CCR6 (0.35) | KCNH2CHRM5F2F10PRSS1 | |
| SCHEMBL10664098 | 0.74 | KCNH2 (0.42) | KCNH2LOXLOXL2F2F10 | |
| SCHEMBL10360899 | 0.74 | MEN1 (0.39) | KCNH2LOXL2CHRM5F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |