⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060459 | 0.79 | ALDH1A1 (1.00) | — | |
| SCHEMBL10001 | 0.79 | — | — | |
| SCHEMBL94975 | 0.79 | — | — | |
| SCHEMBL96499 | 0.76 | — | — | |
| SCHEMBL27584016 | 0.75 | — | — | |
| SCHEMBL27722569 | 0.75 | — | — | |
| SCHEMBL11615492 | 0.75 | — | — | |
| SCHEMBL6669487 | 0.75 | — | — | |
| SCHEMBL6801343 | 0.75 | — | — | |
| SCHEMBL5613577 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105248416-A | Application of low-melting-point cosolved substance in green pesticide solvent and low-melting-point cosolved substance | SHAANXI RES DESIGN INST PETROLEUM CHEMICAL INDUSTR | 2016-01-20 | — | — | CN | claimed |
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8148537-B2 | Substituted acetophenones useful as PDE4 inhibitors | LEO PHARMA A/S (DK) | 2012-04-03 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| EP-2125736-B1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA AS (DK) | 2011-03-30 | — | — | EP | claimed |
| US-20100035908-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA (DK) | 2010-02-11 | — | — | US | claimed |
| EP-2125736-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | Leo Pharma A/S (DK) | 2009-12-02 | — | — | EP | claimed |
| WO-2008077404-A1 | SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS | LEO PHARMA A/S (DK) | 2008-07-03 | — | — | WO | claimed |
| CN-1258497-A | Polymer using in formula of cosmetics | BASF AG (DE) | 2000-07-05 | — | — | CN | claimed |
| US-4119777-A | BY OXIDATION OF A THIOAMIDE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-10 | — | — | US | claimed |
| JP-9053094-A | — | — | None | — | — | JP | disclosed |
| CN-110114358-B | Novel compound and pharmacologically acceptable salt thereof | 明治制果药业株式会社 | 2021-12-03 | — | — | CN | disclosed |
| EP-3099683-B1 | QUINONE-MASKED PROBES AS LABELING REAGENTS FOR CELL UPTAKE MEASUREMENTS | PROMEGA CORP (US) | 2020-08-05 | — | — | EP | disclosed |
| EP-3099691-B1 | PRO-SUBSTRATES FOR LIVE CELL APPLICATIONS | PROMEGA CORP (US) | 2019-11-20 | — | — | EP | disclosed |
| US-9927430-B2 | Pro-substrates for live cell applications | PROMEGA CORPORATION (US) | 2018-03-27 | — | — | US | disclosed |
| US-4309432-A | TOPICAL ADMINISTRATION | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1982-01-05 | — | — | US | disclosed |
| EP-0030030-A1 | Derivatives of 2-aminoethanol, processes for their preparation, pharmaceutical compositions containing such compounds and the use the latter | CIBA-GEIGY AG (CH) | 1981-06-10 | — | — | EP | disclosed |
| EP-0015505-A1 | 3-Amino-1,2-propane diols, process for their preparation, pharmaceutical compositions containing them and use thereof | CIBA-GEIGY AG (CH) | 1980-09-17 | — | — | EP | disclosed |
| US-4132436-A | Recording material | FUJI PHOTO FILM CO., LTD. (JP) | 1979-01-02 | — | — | US | disclosed |
| US-4119777-A | BY OXIDATION OF A THIOAMIDE DERIVATIVE | FUJI PHOTO FILM CO., LTD. (JP) | 1978-10-10 | — | — | US | disclosed |