Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23991436 | 0.92 | BRD4 (0.49) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL30478228 | 0.90 | P4HTM (0.60) | KDM4EP4HTMMAPK1 | |
| SCHEMBL29024699 | 0.90 | P4HTM (0.60) | KDM4EP4HTMMAPK1 | |
| Lithium Ion SCHEMBL28659244 | 0.87 | P4HTM (0.49) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL30112031 | 0.87 | MAPK1 (0.68) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL19555959 | 0.87 | MAPK1 (0.68) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL4395941 | 0.84 | L3MBTL1 (0.63) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL25805510 | 0.84 | KDM4E (0.41) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL8824679 | 0.84 | THRB (0.54) | ALDH1A1KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL10228354 | 0.82 | CNR1 (0.57) | KDM4ENPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260323-A | 2,4- and 2,5-substituted pyridine-N-oxides, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-09 | — | — | US | disclosed |