Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19257463 | 0.77 | THRB (0.43) | THRBLMNAALDH1A1TDP1AGTR1 | |
| SCHEMBL11274872 | 0.77 | THRB (0.43) | THRBLMNAALDH1A1TDP1AGTR1 | |
| SCHEMBL10581335 | 0.76 | THRB (0.71) | THRBLMNAALDH1A1TDP1USP2 | |
| SCHEMBL9742446 | 0.76 | THRB (0.71) | THRBLMNAALDH1A1TDP1USP2 | |
| SCHEMBL2207927 | 0.76 | THRB (0.71) | THRBLMNAALDH1A1TDP1USP2 | |
| SCHEMBL7157355 | 0.76 | THRB (0.71) | THRBLMNAALDH1A1TDP1USP2 | |
| SCHEMBL4122875 | 0.76 | — | — | |
| SCHEMBL19257462 | 0.74 | THRB (0.46) | THRBLMNAALDH1A1TDP1AGTR1 | |
| SCHEMBL19257465 | 0.74 | THRB (0.46) | THRBLMNAALDH1A1TDP1AGTR1 | |
| SCHEMBL735364 | 0.73 | THRB (0.36) | THRBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5220003-A | Process for the synthesis of 2',3'-dideoxynucleosides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-06-15 | — | — | US | claimed |