Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11416046 | 1.00 | NAAA (0.45) | NAAAPKMKMT2AHTTMEN1 | |
| SCHEMBL14302803 | 1.00 | NAAA (0.45) | NAAAPKMKMT2AHTTMEN1 | |
| SCHEMBL9561967 | 1.00 | NAAA (0.45) | NAAAPKMKMT2AHTTMEN1 | |
| SCHEMBL9792913 | 1.00 | NAAA (0.45) | NAAAPKMKMT2AHTTMEN1 | |
| SCHEMBL9561965 | 1.00 | NAAA (0.45) | NAAAPKMKMT2AHTTMEN1 | |
| SCHEMBL11405933 | 0.99 | HTT (0.46) | NAAAPKMKMT2AHTTMEN1 | |
| SCHEMBL11413886 | 0.99 | HTT (0.46) | NAAAPKMKMT2AHTTMEN1 | |
| SCHEMBL11412017 | 0.99 | HTT (0.46) | NAAAPKMKMT2AHTTMEN1 | |
| SCHEMBL11405778 | 0.99 | HTT (0.46) | NAAAPKMKMT2AHTTMEN1 | |
| SCHEMBL11412325 | 0.98 | PKM (0.46) | NAAAPKMKMT2AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236620-A | 2,3-DIFLUOROBENZENE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-08-17 | — | — | US | disclosed |
| US-5055224-A | LIQUID CRYSTAL PHASE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |