Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CHRND | Q07001 | 6/20 | 0.43 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.43 |
| ▸ | CHRNG | P07510 | 2/20 | 0.43 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449626 | 0.76 | MME (0.53) | CA2CA1KMT2AMME | |
| SCHEMBL29822475 | 0.75 | MME (0.56) | CA2CA1CHRNDCHRNA1CHRNG | |
| SCHEMBL3972183 | 0.74 | EGFR (0.63) | ALDH1A1DHFRTSHRSMN1; SMN2TDP1 | |
| SCHEMBL30367266 | 0.74 | ENPEP (0.52) | CA2CA1CHRNDCHRNA1CHRNG | |
| SCHEMBL7110125 | 0.74 | ACE (0.60) | CA2CA1CHRNDCHRNA1CHRNG | |
| SCHEMBL479126 | 0.74 | ACE (0.60) | CA2CA1CHRNDCHRNA1CHRNG | |
| SCHEMBL4386989 | 0.74 | PTPN2 (0.52) | CA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL479125 | 0.74 | ACE (0.60) | CA2CA1CHRNDCHRNA1CHRNG | |
| SCHEMBL5594950 | 0.74 | PTPN2 (0.52) | CA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL3459805 | 0.74 | ACE (0.60) | CA2CA1CHRNDCHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539530-A4 | PURIFICATION DIRECTED CLONING OF PEPTIDES. | — | 1993-09-15 | — | — | EP | disclosed |
| EP-0539530-A1 | PURIFICATION DIRECTED CLONING OF PEPTIDES | BIONEBRASKA, INC. (US) | 1993-05-05 | — | — | EP | disclosed |
| WO-1992001707-A1 | PURIFICATION DIRECTED CLONING OF PEPTIDES | BIONEBRASKA, INC. (US) | 1992-02-06 | — | — | WO | disclosed |