Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214155 | 0.81 | KMT2A (0.49) | KMT2AHTR2AHTR2CHTR2BTP53 | |
| SCHEMBL4555644 | 0.76 | CYP3A4 (0.35) | KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11635434 | 0.74 | KMT2A (0.44) | KMT2AHTR2AHTR2CHTR2BTP53 | |
| SCHEMBL16239248 | 0.72 | ADRA1A (0.36) | HTR2CHTR2BTSHRKDM1ASLC6A2 | |
| SCHEMBL3458407 | 0.70 | CYP2C19 (0.56) | KMT2AHTR2CHTR2BTAAR1LMNA | |
| SCHEMBL29560858 | 0.70 | TAAR1 (0.47) | KMT2AHTR2AHTR2CHTR2BTP53 | |
| SCHEMBL938227 | 0.70 | TAAR1 (0.47) | KMT2AHTR2AHTR2CHTR2BTP53 | |
| SCHEMBL29560461 | 0.70 | TAAR1 (0.47) | KMT2AHTR2AHTR2CHTR2BTP53 | |
| SCHEMBL438926 | 0.70 | HTR2A (0.41) | KMT2AHTR2AHTR2CHTR2BTP53 | |
| SCHEMBL4292448 | 0.70 | TAAR1 (0.47) | KMT2AHTR2AHTR2CHTR2BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5262556-A | Alkylation or hydroxyalkylation by deprotonation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-11-16 | — | — | US | disclosed |