Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | PPIA | P62937 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20592264 | 0.83 | TSHR (0.39) | ADRA1ATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29537759 | 0.73 | ADRA1A (0.43) | ADRA1ATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1499246 | 0.73 | ADRA1A (0.43) | ADRA1ATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4555644 | 0.72 | CYP3A4 (0.35) | ALDH1A1 | |
| SCHEMBL30403864 | 0.72 | MAPK1 (0.39) | ADRA1ATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9562043 | 0.72 | KMT2A (0.45) | TSHRSLC6A2SLC6A3KDM1AALDH1A1 | |
| SCHEMBL10484118 | 0.69 | GRM2 (0.39) | ADRA1ATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23375447 | 0.69 | KDM1A (0.46) | SLC6A2SLC6A4SLC6A3MAPK1KDM1A | |
| SCHEMBL14745937 | 0.69 | HTR2C (0.37) | ADRA1ATSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29580963 | 0.69 | ADRA1A (0.49) | ADRA1ATSHRDRD4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889864-B2 | Metal complexes of cyclometallated imidazo[1,2-f]phenanthridine and diimidazo[1,2-a:1′,2′-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof | UNIVERSAL DISPLAY CORPORATION (US) | 2014-11-18 | — | — | US | disclosed |